Specifications

Complete specifications for PTFE filter holders. Items marked Customizable available upon request.

Size (mm)	Membrane Diameter (mm)	Typical Use
25	25	Micro-filtration, HPLC solvent
40	40	Micro-filtration, small samples
47	47	Routine lab filtration (most common)
90	90	Large sample filtration

Custom sizes available upon request.

📌 Customization Options:
• Material Upgrade: PFA (translucent, visible contents, lower metal leaching)
• Custom Sizes: Non-standard membrane diameters available
• Sealing Type: Threaded / Snap-fit / Quick-release
• Custom specifications available upon request — consult our technical team

Product Description

I. Overview

The PTFE filter holder is precision-machined from high-purity PTFE resin for securing and supporting membranes in filtration operations. Consisting of upper and lower sections that clamp together via threads or snap-fit, the holder securely positions the membrane to ensure that liquid passes only through the membrane — no edge leakage.

Compared to stainless steel or plastic filter holders, PTFE offers overwhelming chemical resistance — compatible with hydrofluoric acid, aqua regia, concentrated sulfuric and nitric acids, and virtually all aggressive reagents — without surface degradation or sample contamination. PTFE's non-stick properties ensure easy membrane replacement and residue-free cleaning.

Available in 25mm, 40mm, 47mm, and 90mm sizes — compatible with all standard membrane diameters. Widely used in pharmaceutical, chemical, semiconductor, and environmental testing laboratories.

II. Core Performance Parameters

Purity: High-purity PTFE with ultra-low metal leaching (Pb, U < 0.01ppb)
Operating Temperature: -196℃ ~ 260℃, short-term up to 300℃
Surface Energy: 18.5 mN/m (lowest among solid materials)
Chemical Resistance: Resistant to HF, aqua regia, concentrated H₂SO₄, HNO₃, strong alkalis, organic solvents
Surface: Non-stick, low friction, easy membrane replacement
Sterilization: Autoclavable (121℃, 2bar) or dry heat sterilization

III. Material & Workmanship

Manufactured from imported high-purity PTFE resin using precision machining in cleanroom environments — ensuring a dense, smooth, dimensionally accurate product. The upper and lower sections are precisely matched with smooth sealing surfaces for uniform clamping and leak-free operation.

Each product undergoes rigorous visual and dimensional inspection to ensure precision and surface quality.

Applications

Typical Applications

HPLC Solvent Filtration

Filtering mobile phase and samples — protects columns

Micro-Filtration

Filtering small volume samples

Sample Pretreatment

Filtration for analytical testing

Microbiological Testing

Membrane filtration for microorganism retention

Particle Analysis

Collecting and analyzing particles in liquids

Corrosive Operations

Safe filtration in strong acid/base environments

Industries

Pharmaceutical Solvent filtration, sample prep
Chemistry Labs Corrosive sample filtration
Semiconductor Chemical filtration, wet processing
Environmental Testing Water sample filtration, particle analysis
Research General laboratory filtration operations

Chemical	PTFE Compatibility	Recommended Temperature	Notes
Hydrofluoric Acid (HF)	✅ Fully Compatible	≤ 250℃	PTFE is the only reliable material
Aqua Regia	✅ Fully Compatible	≤ 200℃	Avoid extreme conditions
Conc. H₂SO₄ (98%)	✅ Fully Compatible	≤ 250℃	Handle with care when heating
Conc. HNO₃ (65%)	✅ Fully Compatible	≤ 250℃	Store away from light
NaOH (50%)	✅ Fully Compatible	≤ 200℃	Safe handling required for concentrated alkalis
Organic Solvents	✅ Fully Compatible	≤ Solvent BP	Ensure ventilation and fire safety

Selection Guide

I. By Membrane Diameter

Membrane Diameter	Recommended Size	Typical Use
25mm	25mm	HPLC solvent, micro samples
40mm	40mm	Micro-filtration, small samples
47mm	47mm	Routine lab filtration
90mm	90mm	Large samples, industrial

II. By Filtration Volume

25mm-40mm: Filtration volume < 50ml
47mm: Filtration volume 50ml ~ 500ml
90mm: Filtration volume > 500ml

III. Sealing Mechanism

Threaded: Reliable sealing for high-pressure or vacuum filtration
Snap-fit: Quick assembly — ideal for frequent membrane changes

💡 Selection Tip: 47mm is the most common lab size — compatible with most standard membranes. Choose this as your default.
For HPLC solvent filtration, choose the 25mm size with syringe filters.
For corrosive samples, always choose PTFE filter holders for reliable long-term operation.
For high-temperature applications, choose the threaded design for more reliable sealing.

Operation & Maintenance

User Guide

Standard operating guidelines for PTFE filter holders. Proper use and maintenance ensure filtration efficiency and product longevity.

I. Pre-use Preparation

Inspect all components — ensure sealing surfaces are smooth
Clean with ultrapure water or appropriate solvent to remove manufacturing residues
Select appropriate membrane (slightly larger than the sealing surface diameter)
Confirm the filter holder is compatible with the receiving vessel or filtration system

II. Membrane Installation

Open the filter holder — place the membrane on the bottom sealing surface
Close the top section — tighten via threads or snap-fit for uniform clamping
Connect to the filtration system (syringe, vacuum pump, or pressure source)
Slowly introduce the liquid — begin filtration

III. Membrane Replacement

After filtration, open the filter holder and remove the used membrane
Clean the sealing surfaces with ultrapure water or appropriate solvent
Inspect sealing surfaces for scratches or damage
Ensure surfaces are dry and clean before installing a new membrane

IV. Cleaning & Maintenance

Clean with ultrapure water or appropriate solvent after use — PTFE's non-stick surface makes cleaning easy
Stubborn residues may be soaked in dilute nitric acid
Sterilization: Autoclave (121℃, 15-20min) or dry heat sterilization
Never use hard brushes or abrasives — they may scratch sealing surfaces

V. Important Notes

PTFE is relatively soft — avoid dropping or impact with hard objects
Do not use for high-temperature operations (> 260℃)
Avoid contact with molten alkali metals (Na, K) and elemental fluorine
Apply moderate clamping force — over-tightening may damage the membrane or sealing surface

💡 From a Seasoned Lab Technician: "Center the membrane — clamp evenly" — Ensure the membrane is centered and fully covers the sealing surface. Apply even pressure when clamping to prevent leakage or membrane damage from wrinkles.
Wet the membrane with a small amount of solvent before filtration to improve efficiency and prevent drying.
For viscous liquids, increase pressure or use a larger diameter filter holder.
Clean immediately after each use to prevent residue buildup.

Care & Notes

Show care & notes

⚠️ Safety & Compliance Checklist

Pressure Safety

Ensure system pressure is within safe limits

Chemical Safety

Corrosive liquid filtration must be performed in a fume hood

PPE

Safety goggles, lab coat, acid/alkali resistant gloves required

Compliance

All operations should follow laboratory safety guidelines

PTFE Filter Holder

Specifications

Product Description

I. Overview

II. Core Performance Parameters

III. Material & Workmanship

Applications

HPLC Solvent Filtration

Micro-Filtration

Sample Pretreatment

Microbiological Testing

Particle Analysis

Corrosive Operations

Selection Guide

I. By Membrane Diameter

II. By Filtration Volume

III. Sealing Mechanism

User Guide

I. Pre-use Preparation

II. Membrane Installation

III. Membrane Replacement

IV. Cleaning & Maintenance

V. Important Notes

Care & Notes

Pressure Safety

Chemical Safety

PPE

Compliance

Need PTFE Filter Holders?

PTFE Filter Holder

Specifications

Product Description

I. Overview

II. Core Performance Parameters

III. Material & Workmanship

Applications

HPLC Solvent Filtration

Micro-Filtration

Sample Pretreatment

Microbiological Testing

Particle Analysis

Corrosive Operations

Selection Guide

I. By Membrane Diameter

II. By Filtration Volume

III. Sealing Mechanism

User Guide

I. Pre-use Preparation

II. Membrane Installation

III. Membrane Replacement

IV. Cleaning & Maintenance

V. Important Notes

Care & Notes

Pressure Safety

Chemical Safety

PPE

Compliance

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